The Cytokeratin 10 Monoclonal Antibody (CAB4669) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is highly specific and reacts with cytoskeletal proteins in human samples, making it a reliable choice for immunohistochemistry and immunofluorescence studies.Cytokeratin 10 is involved in maintaining the structural integrity of epithelial tissues and its expression is often altered in various dermatological conditions and cancers. By using the Anti-Cytokeratin 10 Antibody, researchers can accurately detect and analyze the distribution of this protein in different cell types and tissues, advancing our understanding of its role in skin biology and disease pathogenesis.
This antibody is validated for use in ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Cytokeratin 10 Monoclonal Antibody
SKU:
CAB4669
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC1084
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.
Purification Method
Affinity purification
Gene ID
3858
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Confocal imaging of paraffin-embedded Human skin using Cytokeratin 10 Rabbit mAb (CAB4669, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007, dilution 1:500) (Red). DAPI was used for nuclear staining (Blue). Objective: 40x.Perform high pressure antigen retrieval with 0.01M citrate buffer (pH 6.0) prior to IF staining.
Confocal imaging of paraffin-embedded Mouse skin using Cytokeratin 10 Rabbit mAb (CAB4669, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007, dilution 1:500) (Red). DAPI was used for nuclear staining (Blue). Objective: 40x.Perform high pressure antigen retrieval with 0.01M citrate buffer (pH 6.0) prior to IF staining.
