Lazatatug Antibody is a research-grade biosimilar antibody targeting FOLR1. It is a human IgE, kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry and functional assays. Endotoxin: < 10 EU/mg. Purity: >95% as determined by SDS-PAGE. For research use only.
Folate receptor alpha is a ~29 kDa protein. Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Product Name:
Lazatatug Antibody
SKU:
GXBS02666
Size:
100 µg, 1 mg
Target:
FOLR1
Isotype:
IgE, kappa
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FACS, Functional assay
Synonyms:
CAS: 3035565-36-4
Purity:
>95% as determined by SDS-PAGE
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
Regulatory Status:
For research use only.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
