Leucine aminopeptidase (LAP) is a kind of specific hydrolase ubiquitous in animal and plant tissues. It can hydrolyze not only leucine compounds, but also a variety of other amino-amides and polypeptides. When liver cancer, extrahepatic bile duct obstruction, intrahepatic cholestasis, or other intrahepatic space-occupying lesions, as well as liver parenchymal cell damage, LAP enzyme activity increases, and especially in the early stage of liver cancer, the enzyme activity increases sharply. Therefore, the detection of LAP enzyme activity is of certain clinical significance for the diagnosis and treatment of hepatobiliary diseases.
