The LLGL2 Antibody (CAB13323) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in various applications, including Western blotting.LLGL2, also known as lethal giant larvae homolog 2, plays a crucial role in maintaining cell polarity and regulating cell division. Its tumor-suppressive function has been implicated in various types of cancer, making it a promising target for cancer research. By binding to the LLGL2 protein, this antibody enables precise detection and analysis in a wide range of cell types, allowing researchers to further explore the mechanisms underlying cell polarity and tumorigenesis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
LLGL2 Antibody
SKU:
CAB13323
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
Llglh2, 9130006H11Rik, LLGL2
Positive Sample:
Mouse lung, Mouse testis, Rat lung
Cellular Localization:
Cytoplasm.
Calculated MW:
114kDa
Observed MW:
114kDa
Predicted to enable GTPase activator activity; PDZ domain binding activity; and myosin II binding activity. Acts upstream of or within establishment or maintenance of polarity of embryonic epithelium; labyrinthine layer development; and post-embryonic development. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be active in cortical actin cytoskeleton and plasma membrane. Is expressed in several structures, including cardiovascular system; endocrine gland; genitourinary system; gut; and nasal cavity epithelium. Orthologous to human LLGL2 (LLGL scribble cell polarity complex component 2).
Purification Method
Affinity purification
Gene ID
217325
RRID
AB_2760181
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using LLGL2 Rabbit pAb (CAB13323) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
