null

Anti-LMBRD1 Antibody (CAB15866)

SKU:
CAB15866
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 2 Anti-LMBRD1 Antibody CAB15866
  • Immunology Antibodies 2 Anti-LMBRD1 Antibody CAB15866
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-LMBRD1 Antibody
Antibody SKU:CAB15866
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human LMBRD1 (NP_060838.3).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:U-87MG, HeLa, Mouse brain, Mouse lung, Mouse spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human LMBRD1 (NP_060838.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PLNL IKGT RSAA YERL ENTE DIEE VEQH IQTI KSKS KDGR PLPA RDKR ALKQ FEER LRTL KKRE RHLE FIEN SWWT KFCG A
Gene ID:55788
Uniprot:Q9NUN5
Cellular Location:Lysosome membrane, Multi-pass membrane protein
Calculated MW:21kDa/44kDa/53kDa/61kDa
Observed MW:50kDa
Synonyms:LMBRD1, C6orf209, LMBD1, MAHCF, NESI
Background:This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F.
UniProt Protein Function:Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV).
NCBI Summary:This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F.[provided by RefSeq, Oct 2009]
UniProt Code:Q9NUN5
NCBI GenInfo Identifier:261878497
NCBI Gene ID:55788
NCBI Accession:NP_060838.3
UniProt Secondary Accession:Q9NUN5,Q5VUN6, Q86Y70, Q96FW4, Q9BY56, Q9NZD6, A8K204 E1P531,
UniProt Related Accession:Q9NUN5
Molecular Weight:21,394 Da
NCBI Full Name:probable lysosomal cobalamin transporter
NCBI Synonym Full Names:LMBR1 domain containing 1
NCBI Official Symbol:LMBRD1  
NCBI Official Synonym Symbols:NESI; LMBD1; MAHCF; C6orf209  
NCBI Protein Information:probable lysosomal cobalamin transporter
UniProt Protein Name:Probable lysosomal cobalamin transporter
UniProt Synonym Protein Names:HDAg-L-interacting protein NESI; LMBR1 domain-containing protein 1; Nuclear export signal-interacting protein
UniProt Gene Name:LMBRD1  
Anti-LMBRD1 Antibody (CAB15866)Western blot analysis of extracts of various cell lines, using LMBRD1 antibody (CAB15866) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
Anti-LMBRD1 Antibody (CAB15866)Immunofluorescence analysis of L929 cells using LMBRD1 Rabbit pAb (CAB15866) at dilution of 1:100. Blue: DAPI for nuclear staining.

Related Products