Description
MACV Nucleoprotein Recombinant Protein (N-His)
MACV Nucleoprotein Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu564, with an N-terminal His tag. Predicted molecular weight: 65.46 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nucleoprotein is a ~63 kDa protein. Encapsidates the genome, protecting it from nucleases. For research use only.
The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.
| Product Name: | MACV Nucleoprotein Recombinant Protein (N-His) |
| SKU: | GXRP10182 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | MACV |
| Synonyms: | Nucleoprotein, 3.1.13.-, Nucleocapsid protein, Protein N, N |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu564 |
| Calculated MW: | 65.46 kDa |
| UniProt: | P26578 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
