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Anti-MAD2L1BP Antibody (CAB19600)

SKU:
CAB19600
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CMT2
€139 - €419
Frequently bought together:

Description

Product Name:MAD2L1BP Rabbit mAb
Product Code:CAB19600
Size:20uL, 50uL, 100uL
Synonyms:CMT2
Applications:WB, IHC, IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human MAD2L1BP
Applications:WB, IHC, IF
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, HepG2
Immunogen:A synthesized peptide derived from human MAD2L1BP
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:9587
Uniprot:Q15013
Calculated MW:34kDa
Observed MW:37KDa
UniProt Protein Function:MAD2L1BP: May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. Belongs to the MAD2L1BP family.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 6p21.1Cellular Component: cytoplasm; nucleusMolecular Function: protein bindingBiological Process: mitotic cell cycle checkpoint; regulation of exit from mitosis
UniProt Protein Details:
NCBI Summary:The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
UniProt Code:Q15013
NCBI GenInfo Identifier:3123048
NCBI Gene ID:9587
NCBI Accession:Q15013.1
UniProt Secondary Accession:Q15013,Q6IBB1, B4DLV3, E9PAT7
UniProt Related Accession:Q15013
Molecular Weight:34,676 Da
NCBI Full Name:MAD2L1-binding protein
NCBI Synonym Full Names:MAD2L1 binding protein
NCBI Official Symbol:MAD2L1BP  
NCBI Official Synonym Symbols:CMT2  
NCBI Protein Information:MAD2L1-binding protein
UniProt Protein Name:MAD2L1-binding protein
UniProt Synonym Protein Names:Caught by MAD2 protein
Protein Family:MAD2L1-binding protein
UniProt Gene Name:MAD2L1BP  
UniProt Entry Name:MD2BP_HUMAN

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