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MEK7 Rabbit Polyclonal Antibody (CAB2186)

SKU:
CAB2186
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
  • Cell Death Antibodies 1 Anti-MAP2K7 Antibody CAB2186
  • Cell Death Antibodies 1 Anti-MAP2K7 Antibody CAB2186
  • Cell Death Antibodies 1 Anti-MAP2K7 Antibody CAB2186
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:MEK7 Rabbit Polyclonal Antibody
SKU:CAB2186
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MEK7 (NP_660186.1).
Sequence:MAAS SLEQ KLSR LEAK LKQE NREA RRRI DLNL DISP QRPR PTLQ LPLA NDGG SRSP SSES SPQH PTPP ARPR HMLG LPST LFTP RSME SIEI DQKL QEIM KQTG YLTI GGQR YQAE INDL ENLG EMGS GTCG QVWK MRFR KTGH VIAV KQMR RSGN KEEN KRIL MDLD VVLK SHDC PYIV QCFG TFIT NTDV FIAM ELMG TCAE KLKK RMQG PIPE RILG KMTV AIVK ALYY LKEK HGVI HRDV KPSN IL
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:MEK; MKK7; JNKK2; MEK 7; MAPKK7; PRKMK7; SAPKK4; SAPKK-4; K7
Positive Sample:293T,HeLa,HL-60,Jurkat,PC-3,K-562,Mouse liver,Mouse testis,Mouse brain
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:47kDa
Observed MW:48kDa

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:5609
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using MEK7 antibody (CAB2186) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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