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Key Features

Marstacimab ELISA Kit (GXEL00110)

SKU GXEL00110
Product Type ELISA Kit
Assay Type Quantitative
Detection Method Colorimetric
Sensitivity 0.156 μg/ml
Range 0.31-5 μg/mL
Size 96T
Synonyms PF-06741086, 1985638-39-8
$1,162
Global Shipping: 80+ Countries
White Glove Service: Available upon request
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Distributors: 60+ Countries

Description

Marstacimab ELISA Kit

Assay Genie's Marstacimab ELISA Kit (SKU: GXEL00110) provides researchers with a reliable quantitative ELISA for the quantitative measurement of Marstacimab in Plasma, Serum. Offering a measurement range of 0.31-5 μg/mL and a sensitivity of 0.156 μg/ml, the kit is optimised for precision and ease of use in the research laboratory.

Marstacimab, previously known as PF-06741086, is a fully human monoclonal antibody IgG1 antibody that binds to the K2 domain of TFPI at nanomolar to suprananomolar concentration ranges. Non-clinical experiments demonstrated that marstacimab could enhance thrombin generation in vitro and in vivo in a concentration-dependent manner. In vitro thrombin generation assays (TGAs) and dilute prothrombin time (dPT) assays evaluating Marstacimab added to donor plasma from healthy normal volunteers and patients with haemophilia A, haemophilia B, and haemophilia A with inhibitors have all shown the ability of marstacimab to increase coagulation activity and promote haemostasis. Bleed control was demonstrated in severe injury mice models of haemophilia A and B.

Complete with standards, buffers and detection reagents, the Marstacimab ELISA Kit streamlines assay set-up so you can focus on results. Choose the Marstacimab ELISA Kit from Assay Genie for quality you can trust.

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