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Mouse ADCYAP1 Recombinant Protein (N-GST & C-His)
Key Features

Mouse ADCYAP1 Recombinant Protein (N-GST & C-His) (GXRP07786)

SKU GXRP07786
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-GST & C-His
$458 - $2,412

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Description

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Mouse ADCYAP1 Recombinant Protein (N-GST & C-His)

Mouse ADCYAP1 Recombinant Protein (N-GST & C-His) is a recombinant protein expressed in E. coli, spanning Arg79-Arg171, with an N-terminal GST tag and a C-terminal His tag. Predicted molecular weight: 38.77 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) is a ~19 kDa protein. PACAP is a neuropeptide involved in diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR2), and PACAP type I receptor (ADCYAP1R1). For research use only.

Exerts neuroprotective and general cytoprotective effects due to anti-apoptotic, anti-inflammatory, and antioxidant actions. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.

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