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Mouse Adiponectin/ACRP30 Recombinant Protein (C-His)
Key Features

Mouse Adiponectin/ACRP30 Recombinant Protein (C-His) (GXRP03607)

SKU GXRP03607
Product Type Recombinant Protein
Species Mouse
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Mouse Adiponectin/ACRP30 Recombinant Protein (C-His)

Mouse Adiponectin/ACRP30 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Asn247, with a C-terminal His tag. Predicted molecular weight: 27.78 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Adiponectin (ADPN) is a ~26 kDa protein. Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. For research use only.

Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

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