Description
Mouse ALDH1A1 Recombinant Protein (N-His)
Mouse ALDH1A1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys36-Gly271, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Aldehyde dehydrogenase 1A1 is a ~54 kDa protein. Cytosolic dehydrogenase that catalyzes the irreversible oxidation of a wide range of aldehydes to their corresponding carboxylic acid. For research use only.
Functions downstream of retinol dehydrogenases and catalyzes the oxidation of retinaldehyde into retinoic acid, the second step in the oxidation of retinol/vitamin A into retinoic acid. This pathway is crucial to control the levels of retinol and retinoic acid, two important molecules which excess can be teratogenic and cytotoxic (Probable). Also oxidizes aldehydes resulting from lipid peroxidation like (E)-4-hydroxynon-2-enal/HNE, malonaldehyde and hexanal that form protein adducts and are highly cytotoxic. By participating for instance to the clearance of (E)-4-hydroxynon-2-enal/HNE in the lens epithelium prevents the formation of HNE-protein adducts and lens opacification.
| Product Name: | Mouse ALDH1A1 Recombinant Protein (N-His) |
| SKU: | GXRP13964 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | 3-deoxyglucosone dehydrogenase, ALDH-E1, ALHDII, Ahd-2, Ahd2, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, Aldh1, Aldh1a1, EC:1.2.1.19, EC:1.2.1.28, EC:1.2.1.3, EC:1.2.1.36, RALDH 1, RalDH1, Retinal dehydrogenase 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Lys36-Gly271 |
| UniProt: | P24549 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
