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Mouse APOE Recombinant Protein (C-His)
Key Features

Mouse APOE Recombinant Protein (C-His) (GXRP06079)

SKU GXRP06079
Product Type Recombinant Protein
Species Mouse
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Mouse APOE Recombinant Protein (C-His)

Mouse APOE Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Glu19-Gln311, with a C-terminal His tag. Predicted molecular weight: 37.28 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Apolipoprotein E (APOE) is a ~35 kDa protein. APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. For research use only.

APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.

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