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Mouse BCAT2 Recombinant Protein (N-His)
Key Features

Mouse BCAT2 Recombinant Protein (N-His) (GXRP13995)

SKU GXRP13995
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse BCAT2 Recombinant Protein (N-His)

Mouse BCAT2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp36-Val393, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Branched-chain-amino-acid aminotransferase, mitochondrial is a ~44 kDa protein. Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. For research use only.

Branched chain amino acid catabolism plays a role in adipocyte differentiation by providing lipogenic acetyl-CoA pools in differentiated adipocytes. Mechanistically, acetyl-CoA derived from branched chain amino acid catabolism is used by EP300/p300 to acetylate and inhibit PRDM16, thereby preventing adipose tissue browning. May also function as a transporter of branched chain alpha-keto acids.

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