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Mouse CCN3 Recombinant Protein (N-His)
Key Features

Mouse CCN3 Recombinant Protein (N-His) (GXRP14040)

SKU GXRP14040
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse CCN3 Recombinant Protein (N-His)

Mouse CCN3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser50-Ile354, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CCN family member 3 is a ~38 kDa protein. Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival. For research use only.

Acts by binding to integrins or membrane receptors such as NOTCH1. Essential regulator of hematopoietic stem and progenitor cell function. Inhibits myogenic differentiation through the activation of Notch-signaling pathway. Inhibits vascular smooth muscle cells proliferation by increasing expression of cell-cycle regulators such as CDKN2B or CDKN1A independently of TGFB1 signaling.

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