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GenieFluor 647 Anti-Mouse CD11c Antibody [N418] (AGEL0522)

Datasheet MSDS
SKU AGEL0522
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Armenian Hamster
Isotype IgG2a,k
Clone N418
Conjugation AF 647
$132 - $314

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Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 647 Anti-Mouse CD11c Antibody [N418]

The Mouse CD11c Monoclonal Antibody AF647 Conjugated (N418) is a valuable tool for researchers studying immune cells in various biological contexts. Specifically designed for targeting CD11c, a marker predominantly expressed on dendritic cells, this antibody is conjugated with AF647 for enhanced detection sensitivity.Dendritic cells play a crucial role in the initiation of immune responses and are key players in antigen presentation, making CD11c a widely used marker for identifying and studying these cells. The N418 antibody offers high specificity and sensitivity in detecting CD11c, allowing for precise visualization and analysis of dendritic cell populations in tissues and cell cultures.

With its fluorescent conjugation, this antibody is suitable for use in flow cytometry, immunofluorescence microscopy, and other fluorescence-based detection methods. Its reliability and consistent performance make it an essential tool for immunologists, researchers in the field of oncology, and those investigating immune responses in various disease models. Advance your research with the Mouse CD11c Monoclonal Antibody AF647 Conjugated (N418) and gain new insights into the intricate world of dendritic cell biology.

Product Title:GenieFluor 647 Anti-Mouse CD11c Antibody [N418]
SKU:AGEL0522
Size:25µg, 100µg
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor 647 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.
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