Description
Mouse CD121b/IL1R2 Recombinant Protein (C-His)
Mouse CD121b/IL1R2 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Glu355, with a C-terminal His tag. Predicted molecular weight: 40.45 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Interleukin-1 receptor type 2 (CD121b/IL1R2) is a ~45 kDa protein. Non-signaling receptor for IL1A, IL1B and IL1RN. For research use only.
Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN.
| Product Name: | Mouse CD121b/IL1R2 Recombinant Protein (C-His) |
| SKU: | GXRP05415 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, CD121b, Interleukin-1 receptor type 2, membrane form, mIL-1R2, mIL-1RII, Interleukin-1 receptor type 2, soluble form, sIL-1R2, sIL-1RII, Il1r2, Il-1r2, Il1rb |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-Glu355 |
| Calculated MW: | 40.45 kDa |
| UniProt: | P27931 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
