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Biotin Anti-Mouse CD132 Antibody [3E12] (AGEL0106)

SKU:
AGEL0106
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
3E12
Conjugation:
Biotin
Applications:
FC
€119 - €219
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Title:Biotin Anti-Mouse CD132 Antibody [3E12]
SKU:AGEL0106
Size:25µg, 100µg
Clone No:3E12
Synonyms:Cytokine receptor common subunit gamma;Il2rg;Interleukin-2 receptor subunit gamma;IL-2 receptor subunit gamma;IL-2R subunit gamma;IL-2RG;gammaC;p64;CD132;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Biotin Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P34902
Gene ID:16186
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

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