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APC Anti-Mouse CD14 Antibody [Sa14-2] (AGEL1874)

Datasheet MSDS
SKU AGEL1874
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone Sa14-2
Conjugation APC
€108 - €343

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Description

system_update_altDatasheetsystem_update_altMSDS

APC Anti-Mouse CD14 Antibody [Sa14-2]

The Mouse CD14 Monoclonal Antibody APC Conjugated (SA14-2) is a vital tool for researchers studying the CD14 protein, a key component of the innate immune system responsible for recognizing bacterial cell wall components and initiating immune responses. This monoclonal antibody, conjugated with APC for enhanced detection capabilities, specifically targets mouse CD14 and is suitable for flow cytometry applications. It enables precise identification and analysis of CD14-expressing cells in various experimental settings, serving as an essential resource for immunologists and researchers investigating immune responses in infectious diseases, inflammation, and host defense mechanisms.

The high specificity and sensitivity of this antibody make it an indispensable tool for elucidating the role of CD14 in immune regulation and immune-related disorders.

Product Title:APC Anti-Mouse CD14 Antibody [Sa14-2]
SKU:AGEL1874
Size:25µg, 100µg
Clone No:Sa14-2
Synonyms:CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P10810
Gene ID:12475
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.
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