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APC Anti-Mouse CD16/32 Antibody [2.4G2] (AGEL0589)

Datasheet MSDS
SKU AGEL0589
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 2.4G2
Conjugation APC
$129 - $363

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Description

system_update_altDatasheetsystem_update_altMSDS

APC Anti-Mouse CD16/32 Antibody [2.4G2]

The Mouse CD16/32 Monoclonal Antibody (APC-conjugated, 2.4G2) is a specialized tool for researchers in immunology and cell biology. Specifically designed for the detection and analysis of CD16/32, these cell surface molecules are essential in mediating antibody-dependent cell-mediated cytotoxicity (ADCC) and phagocytosis. The antibody offers high reactivity with mouse samples and is conjugated to allophycocyanin (APC), a fluorescent dye commonly used in flow cytometry applications. By binding to CD16/32, this antibody enables precise identification and characterization of these important receptors in various cell types.CD16 and CD32 are crucial components of the immune system, playing key roles in the activation and regulation of immune responses.

Understanding their expression and function is critical in studying processes such as inflammation, infection, and autoimmune diseases. Researchers can utilize this antibody to explore the involvement of CD16/32 in immune signaling pathways, providing insights into potential therapeutic targets for immune-related disorders.For laboratories engaged in investigating immune responses, inflammatory conditions, or therapeutic antibody development, the Mouse CD16/32 Monoclonal Antibody (APC-conjugated, 2.4G2) offers a reliable and specific tool for robust experimental results.

Product Title:APC Anti-Mouse CD16/32 Antibody [2.4G2]
SKU:AGEL0589
Size:25µg, 100µg
Clone No:2.4G2
Synonyms:CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:APC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P08508 P08101
Gene ID:14130,14131
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.
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