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Biotin Anti-Mouse CD19 Antibody [1D3] (AGEL0002)

Datasheet MSDS
SKU AGEL0002
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2a
Clone 1D3
Conjugation Biotin
Applications FC
$45 - $136

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Description

system_update_altDatasheetsystem_update_altMSDS

Biotin Anti-Mouse CD19 Antibody [1D3]

The Mouse CD19 Monoclonal Antibody, Biotin Conjugated (1D3) is engineered for research involving CD19, a vital cell surface molecule essential for B-cell development and differentiation. This antibody, produced in mice, is highly specific to mouse CD19 and validated for use in flow cytometry applications. Its biotin conjugation enables enhanced detection and quantification in various assay systems, making it ideal for studies in immunology and oncology research.CD19 is a critical marker for B-cell identification and plays a significant role in B-cell signal transduction. The Mouse CD19 Monoclonal Antibody, Biotin Conjugated (1D3), facilitates precise detection and analysis of B-cells, supporting research into B-cell malignancies such as lymphomas and leukemias, as well as autoimmune disorders like rheumatoid arthritis and lupus.

Understanding the function and activity of CD19 is crucial for developing targeted therapies that modulate B-cell function. This antibody is an invaluable tool for researchers aiming to explore the mechanisms of B-cell physiology and pathophysiology, driving advancements in the treatment of B-cell-related diseases.

Product Title:Biotin Anti-Mouse CD19 Antibody [1D3]
SKU:AGEL0002
Size:25µg, 100µg
Clone No:1D3
Synonyms:B-lymphocyte antigen CD19;Cd19;Differentiation antigen CD19;CD19;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Biotin Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P25918
Gene ID:12478
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.
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