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Purified Anti-Mouse CD209b Antibody [22D1] (AGEL0125)

Datasheet MSDS
SKU AGEL0125
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Hamster
Isotype IgG
Clone 22D1
Conjugation Unconjugated
Applications FC
Applications IHC
Applications IP
$33 - $83

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Description

system_update_altDatasheetsystem_update_altMSDS

Purified Anti-Mouse CD209b Antibody [22D1]

The Mouse CD209b Monoclonal Antibody (22D1) is a specialized tool for researchers investigating CD209b, a cell surface receptor involved in immune responses and pathogen recognition. This monoclonal antibody, produced through advanced techniques, exhibits high specificity and affinity for mouse CD209b, enabling precise detection and characterization in experimental settings.CD209b, also known as DC-SIGNR, is a key player in the immune system, particularly in recognizing and binding to pathogens for subsequent immune responses. Its role in modulating immune reactions and potential implications in infectious diseases and immune disorders make it a compelling target for in-depth study.

By utilizing the Mouse CD209b Monoclonal Antibody (22D1), researchers can delve into the functions and regulatory mechanisms of CD209b, paving the way for insights into immune responses and potential therapeutic avenues.This antibody is well-suited for various applications, including immunofluorescence, flow cytometry, and immunohistochemistry, offering versatility in experimental design and analysis. With its proven efficacy and specificity in targeting mouse CD209b, this monoclonal antibody is an invaluable asset for immunologists, microbiologists, and researchers exploring the intricate workings of the immune system.

Product Title:Purified Anti-Mouse CD209b Antibody [22D1]
SKU:AGEL0125
Size:25µg, 100µg
Clone No:22D1
Synonyms:CD209 antigen-like protein B;Cd209b;DC-SIGN-related protein 1;DC-SIGNR1;OtB7;CD209;Cd209b;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Purified Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q8CJ91
Gene ID:69165
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
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