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GenieFluor 488 Anti-Mouse CD25 Antibody [PC-61.5.3] (AGEL1312)

Datasheet MSDS
SKU AGEL1312
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone PC-61.5.3
Conjugation AF 488
$132 - $314

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Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 488 Anti-Mouse CD25 Antibody [PC-61.5.3]

The Mouse CD25 Monoclonal Antibody (AF488 Conjugated, PC 61.5.3) is a vital tool for researchers studying immune responses and T cell biology. This antibody specifically targets CD25, a cell surface receptor involved in the activation and proliferation of T cells, making it essential for understanding immune regulation and tolerance.Derived from mouse monoclonal antibodies, this product is conjugated with AF488 for easy visualization and detection in flow cytometry, immunofluorescence, and other assays. Its high specificity and sensitivity ensure reliable results when studying CD25 expression in various cell types, particularly T cells.CD25, also known as interleukin-2 receptor alpha chain, is a key component in the formation of the high-affinity IL-2 receptor complex, crucial for T cell activation and regulatory T cell function.

By targeting CD25 with this antibody, researchers can explore the role of T cells in immune responses, tolerance mechanisms, and autoimmune disorders.Studies utilizing the Mouse CD25 Monoclonal Antibody (AF488 Conjugated, PC 61.5.3) can pave the way for new insights into immune system function and potential therapeutic targets for conditions involving dysregulated T cell responses. This antibody is a valuable tool for advancing research in immunology, autoimmunity, and cancer immunotherapy.

Product Title:GenieFluor 488 Anti-Mouse CD25 Antibody [PC-61.5.3]
SKU:AGEL1312
Size:25µg, 100µg
Clone No:PC-61.5.3
Synonyms:Interleukin-2 receptor subunit alpha;IL2RA;IL-2 receptor subunit alpha;IL-2-RA;IL-2R subunit alpha;IL2-RA;TAC antigen;p55;p55;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:Genie Fluor 488 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P01590
Gene ID:16184
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD25 is a 55 kD glycoprotein, also known as the low affinity IL-2Rα, Ly-43, p55, or Tac. It is expressed on activated T and B cells, thymocyte subset, pre-B cells, and T regulatory cells. In association with CD122 (IL-2Rβ) and CD132(common γ chain), CD25 forms the high affinity signaling IL-2 receptor.
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