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Mouse CD332/FGFR2 Recombinant Protein (C-His)
Key Features

Mouse CD332/FGFR2 Recombinant Protein (C-His) (GXRP08995)

SKU GXRP08995
Product Type Recombinant Protein
Species Mouse
Expression System Mammalian cells
Tag C-His
$577 - $4,138

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Description

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Mouse CD332/FGFR2 Recombinant Protein (C-His)

Mouse CD332/FGFR2 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Pro263, with a C-terminal His tag. Predicted molecular weight: 30.35 kDa. Purity: >95% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Fibroblast growth factor receptor 2 is a ~91 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. For research use only.

Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4.

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