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PE Anti-Mouse CD335 Antibody [29A1.4] (AGEL1937)

Datasheet MSDS
SKU AGEL1937
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Applications FC
$165 - $462

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Description

system_update_altDatasheetsystem_update_altMSDS

PE Anti-Mouse CD335 Antibody [29A1.4]

The Mouse CD335 Monoclonal Antibody PE-conjugated (29A1.4) is a cutting-edge tool for researchers studying natural killer cell biology and immunology. This high-quality monoclonal antibody specifically targets the CD335 protein, also known as NKp46, a key marker for natural killer cells. The PE conjugation allows for easy and sensitive detection using flow cytometry, making it an excellent choice for analyzing NK cell populations in various experimental settings.Natural killer cells are a vital component of the innate immune system, playing a crucial role in identifying and eliminating infected or abnormal cells.

The CD335 protein is essential for the activation and function of these cytotoxic cells, making it a valuable target for understanding immune responses in various diseases, including infections, cancer, and autoimmune disorders. By using the Mouse CD335 Monoclonal Antibody PE-conjugated (29A1.4), researchers can gain insights into the role of NK cells in immune surveillance and response, paving the way for innovative therapeutic strategies in immunology and oncology research.

Product Title:PE Anti-Mouse CD335 Antibody [29A1.4]
SKU:AGEL1937
Size:25µg, 100µg
Clone No:29A1.4
Synonyms:Ly94;mAR-1;NK-p46;mNKp46;Lymphocyte antigen 94;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q8C567
Gene ID:17086
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.
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