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Mouse CD366/HAVCR2/TIM-3 Recombinant Protein (C-Strep)
Key Features

Mouse CD366/HAVCR2/TIM-3 Recombinant Protein (C-Strep) (GXRP12199)

SKU GXRP12199
Product Type Recombinant Protein
Species Mouse
Expression System Mammalian cells
Tag C-Strep
$577 - $4,138

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Description

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Mouse CD366/HAVCR2/TIM-3 Recombinant Protein (C-Strep)

Mouse CD366/HAVCR2/TIM-3 Recombinant Protein (C-Strep) is a recombinant protein expressed in mammalian cells, spanning Leu22-Arg191, with a C-terminal Strep tag. Predicted molecular weight: 22.00 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Hepatitis A virus cellular receptor 2 homolog is a ~30 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. For research use only.

Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

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