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PE Anti-Mouse CD38 Antibody [NIMR5] (AGEL2014)

Datasheet MSDS
SKU AGEL2014
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Applications FC
$90 - $268

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Description

system_update_altDatasheetsystem_update_altMSDS

PE Anti-Mouse CD38 Antibody [NIMR5]

The Mouse CD38 Monoclonal Antibody (PE-conjugated, NIMR5) is a specialized tool for studying CD38, a cell surface molecule known for its involvement in immune regulation and cell signaling pathways. This antibody, developed for use in flow cytometry applications, offers high specificity and sensitivity for detecting CD38 expression in mouse samples.CD38 is a multifunctional protein that plays a key role in immune responses, cell adhesion, and calcium signaling. Its dysregulation has been linked to various diseases, including cancer, inflammatory disorders, and autoimmune conditions.

By targeting CD38 with this monoclonal antibody, researchers can investigate its role in disease pathogenesis and potentially identify novel therapeutic targets.With its PE-conjugated format, this antibody provides a convenient and reliable tool for analyzing CD38 expression in different cell populations, making it an invaluable asset for immunology and cancer research studies. By understanding the function of CD38, researchers can gain insights into immune system dynamics and potentially develop new strategies for treating immune-related diseases.

Product Title:PE Anti-Mouse CD38 Antibody [NIMR5]
SKU:AGEL2014
Size:25µg, 100µg
Clone No:NIMR5
Synonyms:ADP-ribosyl cyclase 1;ADPRC 1;CD38;NIM-R5 antigen;2'-phospho-cyclic-ADP-ribose transferase;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P56528
Gene ID:12494
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
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