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PE Anti-Mouse CD62L Antibody [Mel14] (AGEL0090)

Datasheet MSDS
SKU AGEL0090
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2a
Clone Mel14
Conjugation PE
Applications FC
$58 - $124

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Description

system_update_altDatasheetsystem_update_altMSDS

PE Anti-Mouse CD62L Antibody [Mel14]

The Mouse CD62L Monoclonal Antibody (PE Conjugated, MEL14) from Assaygenie (AGEL0090) is a powerful tool designed for research involving the CD62L protein in mice. CD62L, also known as L-selectin, is a cell surface molecule involved in lymphocyte homing and adhesion processes, playing a crucial role in immune responses.This monoclonal antibody, conjugated with phycoerythrin (PE), offers high specificity and sensitivity in detecting CD62L in mouse samples. It is ideal for flow cytometry applications, enabling precise identification and analysis of CD62L-expressing cells in various experimental settings.The CD62L Monoclonal Antibody provides researchers with a reliable method to investigate lymphocyte trafficking, immune cell activation, and homing mechanisms in mice.

Its use in immunology, inflammation, and vaccine development research makes it a valuable tool for understanding immune responses and designing novel therapeutic strategies.By targeting CD62L, researchers can gain insights into immune cell behavior, inflammatory processes, and immune system regulation in murine models. This antibody is a valuable asset for studies focusing on lymphocyte migration, inflammation resolution, and immunotherapy development in the context of infectious diseases, autoimmune disorders, and beyond.

Product Title:PE Anti-Mouse CD62L Antibody [Mel14]
SKU:AGEL0090
Size:50 Tests, 100 Tests, 200 Tests
Clone No:Mel14
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P18337
Gene ID:20343
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.
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