Description
Mouse CD86/B7-2 Recombinant Protein (C-His)
Mouse CD86/B7-2 Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Val26-Glu245, with a C-terminal His tag. Predicted molecular weight: 27.94 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. T-lymphocyte activation antigen CD86 is a ~34 kDa protein. Costimulatory molecule that belongs to the immunoglobulin superfamily that plays an important role in T-lymphocyte activation. For research use only.
Acts as the primary auxiliary signal augmenting the MHC/TCR signal in naive T-cells by acting as a ligand for the CD28 receptor which is constitutively expressed on the cell surface of T-cells. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation.
| Product Name: | Mouse CD86/B7-2 Recombinant Protein (C-His) |
| SKU: | GXRP12527 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | Activation B7-2 antigen, B70, BU63, CD28LG2, CD86, CTLA-4 counter-receptor B7.2, FUN-1, T-lymphocyte activation antigen CD86 |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Val26-Glu245 |
| Calculated MW: | 27.94 kDa |
| UniProt: | P42082 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
