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Mouse CD9 Recombinant Protein (N-GST & C-His)
Key Features

Mouse CD9 Recombinant Protein (N-GST & C-His) (GXRP07726)

SKU GXRP07726
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-GST & C-His
€347 - €1,827

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Description

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Mouse CD9 Recombinant Protein (N-GST & C-His)

Mouse CD9 Recombinant Protein (N-GST & C-His) is a recombinant protein expressed in E. coli, spanning Thr110-Ile193, with an N-terminal GST tag and a C-terminal His tag. Predicted molecular weight: 37.95 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CD9 antigen is a ~25 kDa protein. Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. For research use only.

Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion. In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration. In macrophages, associates with CD9 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles. Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption.

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