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Mouse CEMIP Recombinant Protein (N-His)
Key Features

Mouse CEMIP Recombinant Protein (N-His) (GXRP12216)

SKU GXRP12216
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse CEMIP Recombinant Protein (N-His)

Mouse CEMIP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly176-Val419, with an N-terminal His tag. Predicted molecular weight: 29.96 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cell migration-inducing and hyaluronan-binding protein is a ~153 kDa protein. Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. For research use only.

Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination.

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