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Mouse CX3CL1 Recombinant Protein (N-GST & C-His)
Key Features

Mouse CX3CL1 Recombinant Protein (N-GST & C-His) (GXRP14057)

SKU GXRP14057
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-GST & C-His
€347 - €1,827

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Description

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Mouse CX3CL1 Recombinant Protein (N-GST & C-His)

Mouse CX3CL1 Recombinant Protein (N-GST & C-His) is a recombinant protein expressed in E. coli, spanning Thr40-Lys102, with an N-terminal GST tag and a C-terminal His tag. Predicted molecular weight: 35.35 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Fractalkine is a ~42 kDa protein. Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. For research use only.

The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins.

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