Description
Mouse Epha5 Recombinant Protein (N-His)
Mouse Epha5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser60-Gln305, with an N-terminal His tag. Predicted molecular weight: 29.82 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ephrin type-A receptor 5 is a ~97 kDa protein. Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. For research use only.
The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis.
| Product Name: | Mouse Epha5 Recombinant Protein (N-His) |
| SKU: | GXRP11052 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | BSK, Brain-specific kinase, EC:2.7.10.1, EHK-1, EHK1, EK7, EPH homology kinase 1, EPH-like kinase 7, EPHA5, Ephrin type-A receptor 5, HEK7, TYRO4, hEK7 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser60-Gln305 |
| Calculated MW: | 29.82 kDa |
| UniProt: | Q60629 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
