Description
Mouse ERAP1 Recombinant Protein (N-His)
Mouse ERAP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu45-Asp226, with an N-terminal His tag. Predicted molecular weight: 22.73 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Endoplasmic reticulum aminopeptidase 1 (ERAP1) is a ~106 kDa protein. Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. For research use only.
Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus.
| Product Name: | Mouse ERAP1 Recombinant Protein (N-His) |
| SKU: | GXRP05826 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | Appils, PILS-AP, Aminopeptidase PILS, Arts1, Adipocyte-derived leucine aminopeptidase, VEGF-induced aminopeptidase, Puromycin-insensitive leucyl-specific aminopeptidase, Erap1, Endoplasmic reticulum aminopeptidase 1, A-LAP, ARTS-1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu45-Asp226 |
| Calculated MW: | 22.73 kDa |
| UniProt: | Q9EQH2 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
