Description
Mouse ESR1 Recombinant Protein (N-His)
Mouse ESR1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys306-Pro556, with an N-terminal His tag. Predicted molecular weight: 30.97 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Estrogen receptor is a ~66 kDa protein. Nuclear hormone receptor. For research use only.
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner.
| Product Name: | Mouse ESR1 Recombinant Protein (N-His) |
| SKU: | GXRP14074 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | ER, ER-alpha, Esr, Esr1, Estr, Estra, Estradiol receptor, Estrogen receptor, Nr3a1, Nuclear receptor subfamily 3 group A member 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Lys306-Pro556 |
| Calculated MW: | 30.97 kDa |
| UniProt: | P19785 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
