Description
Mouse FADD Recombinant Protein (N-His)
Mouse FADD Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Pro205, with an N-terminal His tag. Predicted molecular weight: 25.12 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. FAS-associated death domain protein (FADD) is a ~22 kDa protein. Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. For research use only.
The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
| Product Name: | Mouse FADD Recombinant Protein (N-His) |
| SKU: | GXRP07818 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Fadd, Mort1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Pro205 |
| Calculated MW: | 25.12 kDa |
| UniProt: | Q61160 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
