Description
Mouse FUT4 Recombinant Protein (N-His)
Mouse FUT4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg88-Arg433, with an N-terminal His tag. Predicted molecular weight: 42.18 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Alpha-(1,3)-fucosyltransferase 4 is a ~49 kDa protein. Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins. For research use only.
Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins. Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis. In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE.
| Product Name: | Mouse FUT4 Recombinant Protein (N-His) |
| SKU: | GXRP13921 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase, Alpha-(1,3)-fucosyltransferase 4, EC:2.4.1.152, Elft, Fuc-TIV, FucT-IV, Fucosyltransferase 4, Fucosyltransferase IV, Fut4, Galactoside 3-L-fucosyltransferase |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg88-Arg433 |
| Calculated MW: | 42.18 kDa |
| UniProt: | Q11127 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
