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Mouse Gnas Recombinant Protein (N-His)
Key Features

Mouse Gnas Recombinant Protein (N-His) (GXRP13975)

SKU GXRP13975
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse Gnas Recombinant Protein (N-His)

Mouse Gnas Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr683-Leu1037, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas is a ~111 kDa protein. Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). For research use only.

The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins.

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