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Mouse HDAC9 Recombinant Protein (N-His)
Key Features

Mouse HDAC9 Recombinant Protein (N-His) (GXRP07844)

SKU GXRP07844
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse HDAC9 Recombinant Protein (N-His)

Mouse HDAC9 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val37-Pro161, with an N-terminal His tag. Predicted molecular weight: 17.29 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Histone deacetylase 9 (HDAC9) is a ~65 kDa protein. Devoided of intrinsic deacetylase activity, promotes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) by recruiting HDAC1 and HDAC3. For research use only.

Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription, inhibits skeletal myogenesis and may be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter.

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