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Mouse HSPD1 Recombinant Protein (N-His)
Key Features

Mouse HSPD1 Recombinant Protein (N-His) (GXRP06882)

SKU GXRP06882
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse HSPD1 Recombinant Protein (N-His)

Mouse HSPD1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala27-Phe573, with an N-terminal His tag. Predicted molecular weight: 60.25 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. 60 kDa heat shock protein, mitochondrial (HSPD1) is a ~60 kDa protein. Chaperonin implicated in mitochondrial protein import and macromolecular assembly. For research use only.

Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10.

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