Description
Mouse HSPG2 Recombinant Protein (N-His)
Mouse HSPG2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp4190-Ser4383, with an N-terminal His tag. Predicted molecular weight: 23.05 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG2) is a ~469 kDa protein. Anti-angiogenic and anti-tumor peptide that inhibits endothelial cell migration, collagen-induced endothelial tube morphogenesis and blood vessel growth in the chorioallantoic membrane. For research use only.
Blocks endothelial cell adhesion to fibronectin and type I collagen. Anti-tumor agent in neovascularization. Interaction with its ligand, integrin alpha2/beta1, is required for the anti-angiogenic properties. Evokes a reduction in phosphorylation of receptor tyrosine kinases via alpha2/beta1 integrin-mediated activation of the tyrosine phosphatase, PTPN6.
| Product Name: | Mouse HSPG2 Recombinant Protein (N-His) |
| SKU: | GXRP05966 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | HSPG2, Perlecan, Basement membrane-specific heparan sulfate proteoglycan core protein, HSPG, PLC |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp4190-Ser4383 |
| Calculated MW: | 23.05 kDa |
| UniProt: | E9PZ16 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
