Description
Mouse IGFBP5 Recombinant Protein (N-His)
Mouse IGFBP5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu20-Glu271, with an N-terminal His tag. Predicted molecular weight: 30.76 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Insulin-like growth factor-binding protein 5 is a ~30 kDa protein. Multifunctional protein that plays a critical role in regulating the availability of IGFs to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type specific manner. For research use only.
Increases the cell proliferation of osteoblasts, intestinal smooth muscle cells and neuroblastoma cells. Enhances adhesion and survival of epithelial cells but decreases adhesion of mesenchymal cells. Once secreted, acts as a major mediator of mTORC1-dependent feedback inhibition of IGF1 signaling. Also plays a role in the induction of extracellular matrix (ECM) production and deposition independently of its nuclear translocation and binding to IGFs.
| Product Name: | Mouse IGFBP5 Recombinant Protein (N-His) |
| SKU: | GXRP13426 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | IBP-5, IGF-binding protein 5, IGFBP-5, Igfbp-5, Igfbp5, Insulin-like growth factor-binding protein 5 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu20-Glu271 |
| Calculated MW: | 30.76 kDa |
| UniProt: | Q07079 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
