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Mouse IL19 Recombinant Protein (N-His)
Key Features

Mouse IL19 Recombinant Protein (N-His) (GXRP12324)

SKU GXRP12324
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse IL19 Recombinant Protein (N-His)

Mouse IL19 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu25-Ala176, with an N-terminal His tag. Predicted molecular weight: 19.90 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Interleukin-19 is a ~20 kDa protein. Cytokine that functions as an anti-inflammatory and proangiogenic factor. For research use only.

Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL5. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3.

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