Description
Mouse IL28A/IFNL2 Recombinant Protein (N-His)
Mouse IL28A/IFNL2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp20-Val193, with an N-terminal His tag. Predicted molecular weight: 21.98 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Interferon lambda-2 (IL28A/IFNL2) is a ~21 kDa protein. Cytokine with antiviral, antitumour and immunomodulatory activities. For research use only.
Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense.
| Product Name: | Mouse IL28A/IFNL2 Recombinant Protein (N-His) |
| SKU: | GXRP05896 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | Interferon lambda-2, Interleukin-28A, Il28a, Ifnl2, IFN-lambda-2, IL-28A |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp20-Val193 |
| Calculated MW: | 21.98 kDa |
| UniProt: | Q4VK74 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
