Description
Mouse MYOC Recombinant Protein (N-His)
Mouse MYOC Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Cys231-Met490, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Myocilin is a ~55 kDa protein. Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. For research use only.
Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling.
| Product Name: | Mouse MYOC Recombinant Protein (N-His) |
| SKU: | GXRP14027 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | Myoc, Myocilin, Myocilin 20 kDa N-terminal fragment, Myocilin 35 kDa N-terminal fragment, Myocilin, C-terminal fragment, Myocilin, N-terminal fragment, Tigr, Trabecular meshwork-induced glucocorticoid response protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Cys231-Met490 |
| UniProt: | O70624 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
