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Mouse NECTIN2 Recombinant Protein (N-His)
Key Features

Mouse NECTIN2 Recombinant Protein (N-His) (GXRP14018)

SKU GXRP14018
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse NECTIN2 Recombinant Protein (N-His)

Mouse NECTIN2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln32-Arg338, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nectin-2 is a ~57 kDa protein. Modulator of T-cell signaling. For research use only.

Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

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