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Mouse P2RX7 Recombinant Protein (N-His)
Key Features

Mouse P2RX7 Recombinant Protein (N-His) (GXRP09866)

SKU GXRP09866
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Mouse P2RX7 Recombinant Protein (N-His)

Mouse P2RX7 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln52-Asp329, with an N-terminal His tag. Predicted molecular weight: 34.12 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. P2X purinoceptor 7 is a ~68 kDa protein. ATP-gated nonselective transmembrane cation channel. For research use only.

Requires high millimolar-range concentrations of ATP to become activated. ATP binding trigers the rapid opening of the channel and allows Na(+) and Ca(2+) influx and K(+) efflux. Has also the ability to form a large pore in the cell membrane, allowing the passage of large cationic molecules. In microglia, may mediate NADPH transport across the plasma membrane.

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