Description
Mouse PDPN Recombinant Protein (N-His)
Mouse PDPN Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly23-Leu141, with an N-terminal His tag. Predicted molecular weight: 14.76 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Podoplanin is a ~18 kDa protein. Mediates effects on cell migration and adhesion through its different partners. For research use only.
During development plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering CLEC1B activation in platelets and leading to platelet activation and/or aggregation. Interaction with CD9, on the contrary, attenuates platelet aggregation and pulmonary metastasis induced by PDPN. Through MSN or EZR interaction promotes epithelial-mesenchymal transition (EMT) leading to ERZ phosphorylation and triggering RHOA activation leading to cell migration increase and invasiveness.
| Product Name: | Mouse PDPN Recombinant Protein (N-His) |
| SKU: | GXRP14005 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | E11, Glycoprotein 38, Gp38, OTS-8, Ots8, PA2.26 antigen, Pdpn, Podoplanin, Transmembrane glycoprotein E11 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly23-Leu141 |
| Calculated MW: | 14.76 kDa |
| UniProt: | Q62011 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
