Description
Mouse PHAX Recombinant Protein (N-His)
Mouse PHAX Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Pro193-Ala359, with an N-terminal His tag. Predicted molecular weight: 21.46 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Phosphorylated adapter RNA export protein is a ~43 kDa protein. A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. For research use only.
Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
| Product Name: | Mouse PHAX Recombinant Protein (N-His) |
| SKU: | GXRP11749 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Mouse |
| Synonyms: | PHAX, Phosphorylated adapter RNA export protein, RNA U small nuclear RNA export adapter protein, RNUXA |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Pro193-Ala359 |
| Calculated MW: | 21.46 kDa |
| UniProt: | Q9JJT9 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
