Mouse Prolactin Recombinant Protein (RPPB0874)
- SKU:
- RPPB0874
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- P06879
- Research Area:
- Growth Factors & Cytokines
Description
| Product Name: | Mouse Prolactin Recombinant Protein |
| Product Code: | RPPB0874 |
| Size: | 5µg |
| Species: | Mouse |
| Target: | Prolactin |
| Synonyms: | AV290867, Gha1, Prl1a1, Growth hormone a1, Mammotropin, Luterotropic hormone, Lutetropin, PRL. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The Prolactin Mouse solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 20% glycerol.� |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSQPLPICS AGDCQTSLRE LFDRVVILSH YIHTLYTDMF IEFDKQYVQD REFMVKVIND CPTSSLATPE�DKEQALKVPP EVLLNLILSL VQSSSDPLFQ LITGVGGIQE APEYILSRAK EIEEQNKQLL EGVEKIISQA YPEAKGNGIY VWSQLPSLQ�GVDEESKILS LRNTIRCLRR DSHKVDNFLK VLRCQIAHQN NC |
Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation.
Prolactin Mouse produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 222 amino acids (30-228a.a.) and having a molecular mass of 25 kDa. Prolactin Mouse protein is fused to a 23 amino acid His tag at N-terminus and is purified by standard chromatography.
| UniProt Protein Function: | prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family. |
| UniProt Protein Details: | Protein type:Cytokine; Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis Cellular Component: extracellular region; secretory granule Molecular Function:prolactin receptor binding; hormone activity Biological Process: lactation; regulation of JAK-STAT cascade; mammary gland development; maternal behavior; positive regulation of cell proliferation; positive regulation of JAK-STAT cascade; regulation of ossification; positive regulation of epithelial cell proliferation; STAT protein nuclear translocation |
| UniProt Code: | P06879 |
| NCBI GenInfo Identifier: | 130934 |
| NCBI Gene ID: | 19109 |
| NCBI Accession: | P06879.1 |
| UniProt Secondary Accession: | P06879,Q544X8, |
| UniProt Related Accession: | P06879 |
| Molecular Weight: | 25,496 Da |
| NCBI Full Name: | Prolactin |
| NCBI Synonym Full Names: | prolactin |
| NCBI Official Symbol: | Prl�� |
| NCBI Official Synonym Symbols: | Prl1a1; AV290867�� |
| NCBI Protein Information: | prolactin |
| UniProt Protein Name: | Prolactin |
| Protein Family: | Prolactin |
| UniProt Gene Name: | Prl�� |
| UniProt Entry Name: | PRL_MOUSE |
